The Nolan Hearing Lab is based within the Wolfson Sensory Pain and Regeneration Centre (Wolfson SPaRC), which forms part of the world-renowned Institute of Psychiatry, Psychology & Neuroscience at King’s College London. Research at the Wolfson SPaRC spans a wide remit with research groups specialising in chronic pain & migraine, repair & regeneration following spinal injury, neuroinflammation, and hearing loss.

Age-related / adult-onset hearing loss (ARHL) is a complex neurodegenerative disease affecting millions of people worldwide. This is an exciting opportunity for a self-motivated and committed postdoctoral research associate to join the Nolan Hearing Lab and work on a research programme funded by the Wellcome Trust. The overarching objective is to understand the molecular mechanisms that underlie the long-known sex-differences in the maintenance of hearing over the life course and determine if sex-specific molecular pathways can be identified that are suitable as potential drug targets in ARHL.

 

The post-holder will work in the lab of Dr Lisa Nolan to support the development of a single-cell RNA-Seq pipeline for cochlear tissue that is suitable to translate to our various mouse models we currently have running in the lab. There will also be good opportunity to collaborate with other members of the Nolan lab working on aligned projects.

 

The post would suit somebody with solid experience of working with small rodents, mouse cochlear dissection and a strong interest in auditory neuroscience. Expertise in one or more of the following areas is also essential: cell culture/primary cell culture/single-cell or bulk RNA-Seq. An active or previous recipient of an Home Office Personal Licence is also highly desirable.

 

The post is based on Guy’s Campus and will benefit from further support from Dr Pawan Dhami, lead of the Genomics and Single Cell Laboratory at Guy’s Hospital.

 

 

Research staff at King’s are entitled to at least 10 days per year (pro-rata) for professional development. This entitlement, from the Concordat to Support the Career Development of Researchers, applies to Postdocs, Research Assistants, Research and Teaching Technicians, Teaching Fellows and AEP equivalent up to and including grade 7. Visit the Centre for Research Staff Development for more information.